NCT07173140Active, not recruiting
Renal Tumour Imaging Using MRI
A Two Site Pilot Study of Functional and Microstructural Imaging Using Magnetic Resonance Imaging in Patients With Renal Tumours
Source: ClinicalTrials.gov · Last updated 15 Sept 2025
Brief summary (registry, in English)
This study investigates whether new types of MRI scans can tell the difference between different kidney tumours before surgery. Currently, imaging scans can detect kidney tumours and their size, but they aren't effective at determining the tumour type or its aggressiveness. Biopsies are an option, but they are invasive and may miss important cancerous cells. The aim is to use imaging to determine which tumours are aggressive so they can be treated early while avoiding unnecessary treatment of benign tumours. Patients with small renal tumours (≤ 7 cm) who meet the other inclusion and exclusion criteria will be asked to have an additional MRI scan at University College London Hospital prior to surgery. The imaging findings will be compared to the histology result from the removed tumour. In 10 patients the histology will be targeted to a specific location in the tumour based on the imaging. 10 patients will undergo a repeat MRI \<14 d apart to test whether the MRI scans can give the same answer twice (the test repeatability). The study is expected to run for 24 months and is funded by NIHR. The chief investigator for the study is Dr Richard Hesketh.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 18 Aug 2025
- Start date
- 20 Nov 2024
- Primary completion date
- 19 Jun 2025
- Lead sponsor
- University College, London
- Diseases
- Kidney cancer
- NCT number
- NCT07173140
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 20 Nov 2024 to the primary completion date, 19 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous treatment of the renal tumour e.g., ablation, radiotherapy
Other illness
- Contraindication to MRI e.g., cardiac pacemaker
Lab values
- Deranged renal function (eGFR \<30) in the last three months.
Other
- Contraindication to MR contrast agents
- Pregnancy
- Breastfeeding
Who the study is looking for
- Aged 18 and over
- Confirmed renal tumour ≤ 7 cm planned for surgical resection
- Willing and able to provide written informed consent
- Able to lie supine for the duration of an MRI
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University College London Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.