NCT07174362Recruiting
QUAD-HF - Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction <50%
QUAD-HF Registry - A Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction of <50%
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
The QUAD-HF registry is an observational study that would enroll patients in the United Kingdom, who have been newly diagnosed with heart failure and a left ventricular ejection fraction \<50%. We plan to assess clinical outcomes in these patients, such as hospitalization and death, in relation to their diagnosis, implementation of guidelines and type of treatments these patients have received.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 4000 (estimated)
- First submitted
- 12 Sept 2025
- Start date
- 6 Oct 2025
- Primary completion date
- Nov 2030
- Lead sponsor
- Mid and South Essex NHS Foundation Trust
- Diseases
- Heart failure
- NCT number
- NCT07174362
What you commit to
- Study type: Observational
- Planned participants: 4000
- From 6 Oct 2025 to the primary completion date, Nov 2030
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- LVEF 50% or more at time of diagnosis
Other
- Palliative care
- Unable or unwilling to give consent
Who the study is looking for
- Age \>18 years
- Newly diagnosed Heart Failure with a Left Ventricular Ejection Fraction \<50% (≤12 Weeks prior to enrolment).
- Able and willing to consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mid and South Essex NHS Foundation Trust Coordinator of this site? Confirm its status | Basildon | United Kingdom | Recruiting |
| British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow Coordinator of this site? Confirm its status | Glasgow | United Kingdom | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.