NCT07175077Recruiting
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
Source: ClinicalTrials.gov · Last updated 2 Dec 2025
Brief summary (registry, in English)
Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 20 (estimated)
- First submitted
- 5 Sept 2025
- Start date
- 1 Nov 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- University of Missouri-Columbia
- Diseases
- Lung cancer
- NCT number
- NCT07175077
What you commit to
- Study type: Observational
- Planned participants: 20
- From 1 Nov 2025 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient must not have other metastatic malignancies requiring current active treatment.
Other
- Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies.
- Patient must not have a contraindication to gadolinium contrast administration during MR imaging.
- Pregnant patients are excluded. Pregnancy status will be confirmed verbally.
Who the study is looking for
- Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC). • Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease.
- Patient also must not have a history of brain metastases or leptomeningeal disease.
- Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T).
- Patient must be ≥ 18 years of age.
- Patient must have ECOG Performance Status of 0-2
- Patients must be able to tolerate the 7T MRI
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Missouri Coordinator of this site? Confirm its status | Columbia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.