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NCT07176338Active, not recruiting

Role of Metformin in Posterior Capsule Opacification

Lens Epithelial Cell Proliferation in Patients Suffering From Diabetes and Treated With Metformin in Vitro: a Pilot Study

Source: ClinicalTrials.gov · Last updated 16 Sept 2025

Brief summary (registry, in English)

Determination of concentrations of systemically applied metformin in human lens capsule and its ability to lower the proliferation rate of human lens epithelial cells in vitro.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
40 (actual)
First submitted
8 Sept 2025
Start date
12 Oct 2022
Primary completion date
1 Oct 2025
Lead sponsor
Vienna Institute for Research in Ocular Surgery
NCT number
NCT07176338

What you commit to

  • Study type: Interventional
  • Participants enrolled: 40
  • From 12 Oct 2022 to the primary completion date, 1 Oct 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous ocular surgery or trauma regarding cataract surgery
  • Previous vitrectomy

Other illness

  • Diabetes mellitus type I

Age

  • Pregnancy (pregnancy test will be taken in women of reproductive age)

Who the study is looking for

  • Age-related cataract
  • Diabetes mellitus type II
  • Metformin treatment
  • Age 21 or older
  • Written informed consent prior to surgery

Age in the registry: 21 years to 105 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Vienna Institute for Research in Ocular Surgery (VIROS)
Coordinator of this site? Confirm its status
ViennaAustriaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.