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NCT07182032WithdrawnPhase 4

Ketamine in Central Sensitization

Ketamine Use in Central Sensitization: a Study Evaluating the Use of Ketamine in Centrally Sensitized Endometriosis Patients

Source: ClinicalTrials.gov · Last updated 11 May 2026

Reason given: Study never opened

Brief summary (registry, in English)

The purpose of this research study is to see if ketamine infusion during surgery can decrease pain after surgery. Ketamine is a medication commonly used as part of anesthesia during surgery and is approved by the US FDA. Patients will be randomized to either receive standard anesthesia with OR without ketamine. The surgical procedure will be the same regardless of which group patients are randomized to. After surgery, patients will be asked to rate their pain in the post-operative observation unit and at their two-week post-operative visit. No additional visits are required for participation in this study. The investigators estimate the surveys will take approximately 10 minutes to complete.

Status (registry)
Withdrawn
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
0 (actual)
First submitted
16 Sept 2025
Start date
1 Feb 2026
Primary completion date
30 Jun 2028
Lead sponsor
University Hospitals Cleveland Medical Center
NCT number
NCT07182032

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • known allergy or contraindication to ketamine
  • History of substance use disorder, including alcohol or marijuana use, both current and remote
  • History of severe psychiatric illness, including schizoaffective disorder, bipolar disorder, psychosis, or decompensated psychiatric condition , excluding anxiety and depression

Other

  • Current Intraoperative complications

Who the study is looking for

  • age range 18-89
  • ASA classification I-III
  • outpatient elective laparoscopy for endometriosis

Age in the registry: 18 years to 89 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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SiteCityCountrySite status
University Hospitals Cleveland Medical Center*ClevelandUnited StatesUnknown status

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This page is information, not medical advice. Discuss any trial with your doctor.