NCT07182136Completed
The Impact of Hepatic Steatosis on Survival After Pancreaticoduodenectomy
The Impact of Hepatic Steatosis on Survival After Pancreaticoduodenectomy for Resectable Pancreatic Cancer. A Multifactorial Analysis of Metabolic Dysfunction
Source: ClinicalTrials.gov · Last updated 19 Sept 2025
Brief summary (registry, in English)
We will use simple summaries, educational handouts, and discussions with doctors and nurses to explain this study. The study looks at patients with early-stage pancreatic cancer who undergo pancreaticoduodenectomy (Whipple surgery). We found that some patients develop fatty liver (non-alcoholic fatty liver disease, NAFLD) within six months after surgery, which can affect nutrition, blood sugar control, and long-term survival. To help patients and families understand, we will: 1. Provide clear written information sheets about the purpose of the study and its findings. 2. Use diagrams or plain-language explanations of terms like "pancreatic exocrine function" and "fatty liver." 3. Share results with healthcare providers so they can guide patients in nutrition, enzyme replacement, diabetes monitoring, and follow-up care. 4. Offer contact information for the research team to answer questions.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 200 (actual)
- First submitted
- 11 Sept 2025
- Start date
- 1 Jan 2015
- Primary completion date
- 31 Mar 2023
- Lead sponsor
- Wei-Hsun Lu
- NCT number
- NCT07182136
What you commit to
- Study type: Observational
- Participants enrolled: 200
- From 1 Jan 2015 to the primary completion date, 31 Mar 2023
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Death within 6 months after surgery
Other
- Preoperative hepatic steatosis
- Incomplete clinical or imaging data
Who the study is looking for
- Adults with stage I-II pancreatic ductal adenocarcinoma.
- Underwent curative-intent pancreaticoduodenectomy (conventional or pylorus-preserving).
- Surgery between January 2015 and May 2023.
- Complete clinical and imaging data available.
- Survived at least 6 months postoperatively.
Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.