NCT07183124Not yet recruiting
3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin
Using 3D Modeling to Detect Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin
Source: ClinicalTrials.gov · Last updated 19 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This retrospective study aims to develop an AI-assisted 3D modeling system to improve staging accuracy for stage II-III locally advanced rectal cancer (LARC). High-quality CT images from Taichung Veterans General Hospital will be used to reconstruct tumor boundaries and spatial relationships. The AI model will be trained and validated against MRI and pathology results to predict circumferential resection margin (CRM) status. Outcomes include sensitivity, specificity, accuracy, and agreement with standard imaging. This system seeks to support precise tumor staging and inform future clinical decision-making.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 14 Sept 2025
- Start date
- 1 Oct 2025
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Taichung Veterans General Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT07183124
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 1 Oct 2025 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with clinical stage I or IV rectal cancer.
- Presence of other major diseases or malignancies affecting tumor assessment (e.g., diagnosis of another malignancy within the past three years, uncontrolled cardiovascular disease).
Age
- Age under 18 years, or physical status not meeting American Society of Anesthesiologists (ASA) I-III criteria, unable to undergo surgery or related treatment.
Other
- Incomplete medical records or imaging data, including missing required CT or MRI images.
Who the study is looking for
- Diagnosed with rectal cancer, clinical stage II-III, with no distant metastasis (M0)
- Age over 18 years, with adequate physical status classified as American Society of Anesthesiologists (ASA) I-III, capable of receiving treatment and surgery
- No history of other malignancies or major diseases affecting study assessment within the past three years.
- Complete medical records, including available CT and MRI imaging.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taichung Veterans General Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.