NCT07183163Completed
The Role of Obesity in Peri-Implant Health(ROPIPH)
Evaluating the Influence of Obesity on Peri-Implant Health Through Clinical and Biochemical Parameters
Source: ClinicalTrials.gov · Last updated 19 Sept 2025
Brief summary (registry, in English)
This clinical study aims to evaluate the influence of obesity on peri-implant health. Both clinical parameters and biochemical markers in peri-implant crevicular fluid(PICF) will be assessed. The study will include patients with dental implants who are classified as obese as well as a control group of non-obese participants. Clinical outcomes such as probing depth, plaque index, bleeding on probing, and peri-implant bone levels will be recorded. In addition, PICF samples will be analyzed for inflammatory biomarkers including interleukin-1 beta(IL-1beta), tumor necrosis factor-alpha(TNF-alfa), and matrix metalloproteinase-8(MMP-8). The results of this study may help to clarify the relationship between obesity and inflammatory responses in peri-implant tissues.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 5 Sept 2025
- Start date
- 12 Feb 2023
- Primary completion date
- 27 May 2024
- Lead sponsor
- Mine Keskin
- Diseases
- Obesity
- NCT number
- NCT07183163
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 12 Feb 2023 to the primary completion date, 27 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of antibiotics or anti-inflammatory drugs within the last 3 months.
- Patients who had received peri-implant treatment within the last 6 months.
Other illness
- Patients with systemic diseases affecting periodontal/implant health (e.g., uncontrolled diabetes, HIV, cardiovascular disease, kidney disorders).
Other
- Pregnant or lactating women.
- Current smokers or individuals using smokeless tobacco.
- Alcohol abuse.
Who the study is looking for
- Adults ≥18 years with dental implants in function for at least 1 year.
- Patients diagnosed with peri-implantitis according to clinical and radiographic criteria.
- For control group: systemically healthy individuals with peri-implant health.
- Written informed consent obtained.
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Recep Tayyip Erdoğan University Faculty of Dentistry, Department of Periodontology Coordinator of this site? Confirm its status | Rize | Turkey (Türkiye) | Unknown status |
Related publications
- Influence of Obesity on Peri-Implant Health: A Cross-Sectional Clinical and Biochemical Study.Diagnostics (Basel) · 2026 · PMID 41975678
This page is information, not medical advice. Discuss any trial with your doctor.