NCT07190105Completed
Vagal Approaches on Long COVID-19
Impact of Vagal Approaches on Symptomatology in Long COVID Participants
Source: ClinicalTrials.gov · Last updated 7 Jan 2026
Brief summary (registry, in English)
The purpose of this study is to explore whether two general wellness products, alone or combined, can support individuals experiencing Long COVID symptoms. Both wellness products stimulate the vagus nerve - a nerve that helps regulate stress, relaxation, mood, breathing, heart rate, inflammation, and digestion. The investigators will use a Fitbit to track participants' health measurements including, but not limited to, activity, heart rate, and heart rate variability, and participants will be asked to complete surveys about their experience. This information will be collected into a repository where participants can share their experiences with Long COVID symptoms.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 546 (actual)
- First submitted
- 22 Sept 2025
- Start date
- 27 Oct 2025
- Primary completion date
- 11 Dec 2025
- Lead sponsor
- Leidos Life Sciences
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT07190105
What you commit to
- Study type: Interventional
- Participants enrolled: 546
- From 27 Oct 2025 to the primary completion date, 11 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Tested positive by any test for acute COVID-19 and/or have ICD-10 code for COVID-19 in their electronic health records (EHR)
- Any patient having the ICD-10 code for post-acute sequelae of COVID-19 (PASC) within their EHR, or any patient who has evidence of a Long COVID clinic visit within their EHR
- Have persistent COVID-19 symptoms 3 months following resolution of acute COVID-19 infection as indicated by a negative COVID-19 test
- Self-identified as having Long COVID based on symptomology:
- Symptoms must include any combination of the following: (ICD-10 codes shown):
- Shortness of breath (R06.02, R06.00, or R06.09)
- Fatigue (R53.83, or R53.82)
- Cognitive impairment (G31.84 or R41.9)
- Mental, Behavioral, and Neurodevelopmental disorders (F01-F99)
- Postural orthostatic tachycardia syndrome (POTS) (I49.8)
- Participants must have auditory headphones; over the ear headphones or earbuds
- Participants must be at least 18 years of age, inclusive, at the time of signing the informed consent
- Capable of understanding and providing signed informed consent
- Participants must have a smart phone
- Reliable access to internet via browser installed on a smartphone
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Virtual Coordinator of this site? Confirm its status | Frederick | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.