NCT07190846Completed
Diastolic Dysfunction 2025
Diastolic Dysfunction in the Pregnant Woman With Preeclampsia
Source: ClinicalTrials.gov · Last updated 24 Sept 2025
Brief summary (registry, in English)
This is a prospective observational study conducted at the Maternity and Neonatology Center of Tunis to evaluate cardiac diastolic function in women with preeclampsia compared with normotensive pregnant women. A total of 80 pregnant women in the third trimester were enrolled, including 40 with preeclampsia (mostly severe forms) and 40 healthy controls. All participants underwent standardized transthoracic echocardiography to assess left ventricular diastolic function according to the 2016 ASE/EACVI recommendations.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 1 Sept 2025
- Start date
- 1 Mar 2025
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- University Tunis El Manar
- Diseases
- High blood pressure
- NCT number
- NCT07190846
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 1 Mar 2025 to the primary completion date, 31 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known pre-existing cardiovascular disease (structural heart disease, heart failure, chronic hypertension complicated)
- Pre-gestational diabetes
- Chronic kidney disease
- Other severe comorbidities that could affect cardiac function independently of preeclampsia
Lab values
- Left ventricular ejection fraction \< 45%
Other
- Multiple pregnancy
Who the study is looking for
- Pregnant women aged 18-45 years
- Third trimester of pregnancy
- Group A: women diagnosed with preeclampsia according to international criteria (blood pressure ≥ 140/90 mmHg after 20 weeks with proteinuria or signs of severity)
- Group B (controls): normotensive pregnant women without proteinuria or cardiovascular disease
- Signed informed consent
Age in the registry: 18 years to 45 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Maternity and Neonatology Center of Tunis Coordinator of this site? Confirm its status | Tunis | Tunisia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.