NCT07194577Completed
Effect of Moringa Oleifera Dehydrated Leaf Powder on the Components of Metabolic Syndrome in Mexican Adults.
"Effect of Moringa Oleifera Dehydrated Leaf Powder on the Components of Metabolic Syndrome in Mexican Adults. Double-blind Randomized Clinical Trial. Phase II"
Source: ClinicalTrials.gov · Last updated 26 Sept 2025
Brief summary (registry, in English)
Background: The increase in chronic degenerative diseases caused by Metabolic Syndrome (MS) has prompted the search for natural alternatives to develop new medications and to know the mechanism and dosages for their proper use. To date, evidence of the potential use of moringa in the context of metabolic diseases such as diabetes mellitus 2, obesity, and dyslipidemia is available. However, before they can be used as a treatment for metabolic diseases in humans, clinical studies must be carried out to establish the consistency of its medicinal efficacy and the safest modalities of its administration. Objective: To compare the effect of Moringa oleifera dehydrated leaf powder vs a placebo on the components of metabolic syndrome in mexican adults. Material and methods: Double blind randomized clinical trial, phase II. 42 adults diagnosed with MS treated at the family medical consultation of Clinic 19 of the IMSS Colima will be randomly assigned to 2 groups: intervention group (MO powdered leaf capsules, 5.5 grams per day) and placebo group (starch capsules, 5.5 grams per day). The data collected will be weight, height, blood pressure, and waist circumference, and blood tests include glucose, lipid profile \[triglycerides, total cholesterol, HDL cholesterol\], glycosylated hemoglobin. Both groups will be evaluated before starting treatment and 8 weeks later, after completing the treatment. Resources and infrastructure: The laboratory exams will are carried out in HGZ1 no.1 of the IMSS.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 12 May 2025
- Start date
- 5 Jan 2023
- Primary completion date
- 30 Jul 2024
- Lead sponsor
- Universidad de Colima
- Diseases
- Type 2 diabetes
- NCT number
- NCT07194577
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 5 Jan 2023 to the primary completion date, 30 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients on insulin therapy
Other illness
- Conditions that do not allow blood collection
- Patients with metabolic syndrome who currently follow a nutritional plan and/or do exercise
- Patients with hypothyroidism and hyperthyroidism, cancer, renal failure and/or liver cirrhosis
- Patients with any complication of diabetes mellitus
- People with food allergies
- Acute infection in progress at the time of blood sample collection
- Patients who present side effects (nausea, vomiting, diarrhea, stomach pain) or any symptom related to discomfort, allergy or intolerance with the consumption of Moringa oleifera leaf powder that does not disappear in a period of 3 days.
Lab values
- Insufficient, coagulated or hemolyzed serum sample.
Other
- Pregnant women
- Smokers
- People who take botanical extracts or a multivitamin
- Patients must not be participating in another study alternately
- Elimination Criteria
- Patients who interrupt treatment or who do not wish to continue.
Who the study is looking for
- Beneficiaries of the medical consultation of the Instituto Mexicano del Seguro Social (IMSS), Colima
- \- Female and male gender
- People with 3 diagnostic variables of metabolic syndrome according to the standardization of criteria established for the diagnosis of Metabolic Syndrome (2009).
- Patients under treatment for components of metabolic syndrome (dyslipidemia, diabetes, arterial hypertension)
- Signed informed consent
Age in the registry: 25 years to 59 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Unidad de Medicina Familiar No.19, Instituto Mexicano del Seguro Social Coordinator of this site? Confirm its status | Colima | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.