NCT07194811Active, not recruiting
Stroke of Unknown Cause in Women: The Impact of Long-term Heart Monitoring on Stroke Recurrence
Stroke of Unknown Cause: The Impact of Long-term Heart Monitoring on Stroke Recurrence in Women
Source: ClinicalTrials.gov · Last updated 26 Sept 2025
Brief summary (registry, in English)
The goal of this observational study is to investigate sex - differences in detection rate of atrial fibrillation after cryptogenic stroke (embolic stroke of unknown cause) - using an implantable cardiac rhythm monitor - and the treatment effects of oral anticoagulation on recurrent stroke, ischemic cardiovascular events, major bleeding risk, disability and mortality. The main questions to answer are: * Is long-term monitoring and detection of atrial fibrillation after stroke of unknown cause in women related to recurrent stroke and disability? * Is long-term monitoring and initiation of oral anticoagulation related to cardiovascular events and intracranial haemorrhages? And in addition increased in women compared to men? * Is long-term rhythm monitoring after stroke with unknown cause related to patient reported outcomes in women?
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 1400 (estimated)
- First submitted
- 19 Sept 2025
- Start date
- May 2016
- Primary completion date
- Dec 2023
- Lead sponsor
- University Hospital, Akershus
- Diseases
- Stroke, Atrial fibrillation
- NCT number
- NCT07194811
What you commit to
- Study type: Observational
- Planned participants: 1400
- From May 2016 to the primary completion date, Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe cognitive impairment or disability or with a short life expectancy due to comorbidities of less than two years.
Other
- Patients with known or newly detected AF on standard ECG or 24 h Holter ECG.
- Patients on oral anticoagulants (OAC) for non-AF indications
- Patients with strong contraindications for OAC
Who the study is looking for
- Patients diagnosed with cryptogenic stroke or TIA, according to the TOAST (Trial of Org 10172 in Acute Stroke Treatment) classification and an implantable cardiac rythm monitor (ICM) for the ICM group not the control
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Akershus University Hospital, Department of Neurology Coordinator of this site? Confirm its status | Oslo | Norway | Unknown status |
Related publications
- Cryptogenic stroke in women: impact of insertable cardiac monitoring in the STROKEWISE cohort study.Europace · 2026 · PMID 41870212
This page is information, not medical advice. Discuss any trial with your doctor.