NCT07195370Active, not recruiting
Testing YAG Laser Iridotomy for Primary Angle-Closure Glaucoma
Evaluation of the Effectiveness of YAG Laser Iridotomy in Patients With Primary Angle-Closure: Temporal Peripheral Iridotomy Compared to Inferior Peripheral Iridotomy
Source: ClinicalTrials.gov · Last updated 26 Sept 2025
Brief summary (registry, in English)
This study evaluates the effectiveness and safety of YAG laser peripheral iridotomy performed at two different locations (temporal and inferior) in patients with primary angle-closure glaucoma, a leading cause of blindness worldwide. Patients visiting the glaucoma clinic at Feiz Hospital who are candidates for peripheral iridotomy will participate. In each patient, one eye will receive a temporal iridotomy, and the other eye will receive an inferior iridotomy, with patients unaware of the location used in each eye. The study will measure outcomes such as laser power, intraocular pressure, visual symptoms, and complications over six months to determine which approach is more effective and safer.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 26 Aug 2025
- Start date
- 1 May 2025
- Primary completion date
- 1 Oct 2025
- Lead sponsor
- Isfahan University of Medical Sciences
- Diseases
- Glaucoma
- NCT number
- NCT07195370
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 1 May 2025 to the primary completion date, 1 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous eye surgery (except for minor procedures).
Other illness
- Active eye diseases (e.g., infection or inflammation).
- Severe visual impairment (e.g., less than 20/200 vision).
- Uncontrolled systemic diseases (e.g., diabetes or cardiovascular disease).
Other
- Advanced cataracts or lens-related issues.
- Pregnancy or breastfeeding.
- Inability to follow-up with scheduled visits.
- \-
Who the study is looking for
- Adults (typically over 40 years old).
- Ability to provide informed consent.
- Narrow or closed anterior chamber angle (based on gonioscopy).
- Intraocular pressure (IOP) controlled with medication but requiring surgery.
- No previous iridotomy.
Age in the registry: 24 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Isfahan University of Medical Sciences Coordinator of this site? Confirm its status | Isfahan | Iran | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.