NCT07196371Recruiting
Feasibility of Aerobic Exercise With Blood Flow Restriction Training in People Living With Type 2 Diabetes
Testing the Feasibility of Blood Flow Restriction Training to Enhance the Health Benefits of Exercise in Individuals With Type 2 Diabetes: a Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 26 Jan 2026
Brief summary (registry, in English)
The goal of this trial is to learn if blood flow restriction training with treadmill walking is possible for individuals living with type 2 diabetes. It will also learn about how the blood flow restriction with treadmill walking could improve health. The main questions it aims to answer are: Is 6 weeks of treadmill walking with blood flow restriction reasonable for people with type 2 diabetes to perform? Does treadmill walking with blood flow restriction training help manage type 2 diabetes better than just treadmill walking? Researchers will compare treadmill walking with blood flow restriction to treadmill walking without blood flow restriction to see if blood flow restriction works to manage type 2 diabetes based on fitness and blood sugar levels. Participants will: Perform treadmill walking with or without blood flow restriction for 96 minutes a week for 6 weeks. Visit the lab before and after the exercise for tests and questionnaires.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 13 Mar 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- University of New Brunswick
- Diseases
- Type 2 diabetes
- NCT number
- NCT07196371
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Jan 2026 to the primary completion date, 31 Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Unstable medications over the last 3 months
Other illness
- Absolute contraindications to BFR (i.e. peripheral vascular disease)
- A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions
- A diagnosis of any red blood cell-altering condition (i.e., sickle cell anemia, poikilocytosis)
- Currently living with any cardiovascular disease, which would impact the ability to participate in exercise safely
- Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity
Other
- Musculoskeletal issues preventing exercise training
Who the study is looking for
- Diagnosed with type 2 diabetes (5.7% \< HbA1c \< 9.0%)
- Not regularly physically active (150 mins moderate-vigorous physical activity per week)
Age in the registry: 19 years to 64 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiometabolic Exercise & Lifestyle Laboratory Coordinator of this site? Confirm its status | Fredericton | Canada | Recruiting |
| Human Performance & Health Research Laboratory Coordinator of this site? Confirm its status | Guelph | Canada | Recruiting |
| Exercise Metabolism and Inflammation Laboratory Coordinator of this site? Confirm its status | Okanagan | Canada | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.