NCT07201610Not yet recruiting
Non-invasive Diagnosis of Parkinson's Disease
Non-invasive Diagnosis of Parkinson's Disease Using Hyperspectral Retinal Imaging, Optical Coherence Tomography, Computerized Cognitive Testing, and Voice Analysis
Source: ClinicalTrials.gov · Last updated 1 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study will investigate new, non-invasive methods to help diagnose Parkinson's disease. Researchers will use advanced eye imaging (hyperspectral retinal photography and OCT), computerized memory and thinking tests, and voice analysis to identify patterns linked to Parkinson's. The goal is to improve early and accurate diagnosis of Parkinson's disease without the need for spinal taps or invasive tests.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 60 (estimated)
- First submitted
- 12 Sept 2025
- Start date
- 16 Oct 2025
- Primary completion date
- 16 Dec 2025
- Lead sponsor
- Blekinge Institute of Technology
- Diseases
- Lewy body dementia, Parkinson disease
- NCT number
- NCT07201610
What you commit to
- Study type: Observational
- Planned participants: 60
- From 16 Oct 2025 to the primary completion date, 16 Dec 2025
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- At least one eye must not have retinal disease, glaucoma, or vascular eye disease (such as embolism)
- Diagnosed dementia
- No diagnosed or suspected Parkinson's disease
- No diagnosed or suspected cognitive disease
- No psychiatric disease affecting cognition (e.g., psychotic disorder or major depression)
Other
- Angle-closure glaucoma or other contraindication to mydriatic drops
- Low functional ability that makes participation in examinations impossible
- Specifically for the control group: Not healthy according to the definition below
- Definition of healthy:
- Cognitive testing with MMSE ≥ 26 points (out of a maximum of 30) and ≥ 8 points on the clock-drawing test
Who the study is looking for
- Age 60-80 years
- Diagnosis of idiopathic Parkinson's disease
- Ability to understand spoken and written Swedish
- Ability to personally provide consent to participate in the study
- At least one healthy eye for retinal photography
- Age 60-80 years
- Ability to understand spoken and written Swedish
- Ability to personally provide consent to participate in the study
- At least one healthy eye for retinal photography
- Healthy as defined below
Age in the registry: 60 years to 80 years · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.