Fact CheckerSign in

NCT07203287RecruitingPhase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

Source: ClinicalTrials.gov · Last updated 20 Oct 2026

Brief summary (registry, in English)

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

Status (registry)
Recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
490 (estimated)
First submitted
17 Sept 2025
Start date
26 Aug 2025
Primary completion date
31 Dec 2026
Lead sponsor
The University of Texas Medical Branch, Galveston
NCT number
NCT07203287

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 490
  • From 26 Aug 2025 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients presenting for Renal Transplantation
  • The surgery requires intubation post-operatively

Other illness

  • Any patient with end stage renal disease
  • Documented allergy to Rocuronium, Sugammadex, Cisatracurium or Neostigmine

Age

  • Any patient under the age of 18
  • Any patient over the age of 80

Other

  • Any patient requiring dialysis
  • Pregnant Female
  • Any patient in the correctional system
  • Urgent or Emergent procedure

Who the study is looking for

  • The subject is able and willing to provide and sign informed consent
  • The subject must be between 18 and 80 years of age
  • The subject should have chronic kidney disease as defined by glomerular filtration rate
  • The surgery must require general anesthesia with endotracheal intubation and neuromuscular blockade

Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Texas Medical Branch
Coordinator of this site? Confirm its status
GalvestonUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.