NCT07203430Completed
Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise
Assessing Adaptations in Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise Intervention in Individuals With Low Back Pain
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the longitudinal effects of a four-week dynamic resistance training program using the 45-degree Roman chair on pain sensitivity changes after exercise and lumbar muscle performance in individuals with chronic low back pain (LBP). This study will consist of three specific aims. Aim 1 examines changes in local exercise-induced hypoalgesia. Aim 2 will assess changes in lumbar multifidus and erector spinae thickness using ultrasound imaging before and after the intervention. Aim 3 will evaluate changes in lumbar extensor strength (handheld dynamometry (HHD)) and endurance (Biering-Sørensen test).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 22 Sept 2025
- Start date
- 15 Oct 2025
- Primary completion date
- 9 Apr 2026
- Lead sponsor
- University of Central Florida
- NCT number
- NCT07203430
What you commit to
- Study type: Interventional
- Participants enrolled: 22
- From 15 Oct 2025 to the primary completion date, 9 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- current enrollment in physical therapy or structured rehabilitation for LBP,
Other illness
- History of spinal surgery, fusion, or fracture within the past 6 months
- diagnosed degenerative disc disease, scoliosis, or spinal pathology that precludes safe exercise participation
- cardiovascular, pulmonary, metabolic, or systemic disease that increases risk during exercise
- nociplastic pain conditions (e.g., fibromyalgia) or neurological conditions that confound EIH responses
Other
- use of an assistive device for walking (cane, walker) within the past year
- pregnancy, due to contraindications for exercise testing and ultrasound -body weight ≥ 300 lbs., which exceeds the safe capacity of the Roman chair --
- current tobacco/nicotine use
- inability to complete ≥ 8 Roman chair repetitions with proper form during screening
- non-English speaking
Who the study is looking for
- chronic low back pain lasting ≥ 12 weeks
- current pain intensity ≥ 3/10 but no higher than an 8/10 on the Numeric Pain Rating Scale (NPRS) within the past 48 hours
- resistance trained (defined as 2x/week for the past 8-12 weeks)
- able to read and speak English for informed consent and completion of questionnaires
- willing and physically able to complete all testing and intervention sessions.
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Central Florida Coordinator of this site? Confirm its status | Orlando | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.