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NCT07205978Active, not recruiting

Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis

Source: ClinicalTrials.gov · Last updated 20 Mar 2026

Brief summary (registry, in English)

The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest. However, the findings from previous studies have been conflicting for some health outcomes, such as type-2 diabetes, and have been underexplored for other outcomes, such as neurodegenerative diseases. One contributing factor to these inconsistencies lies in the different analytical approaches and confounding factors used across studies. Furthermore, the majority of previous studies have primarily focused on populations in Europe or the United States, potentially limiting the generalizability of the findings to other global regions. The NUTPOOL project aims to address these gaps by conducting an extensive individual participant data (IPD) meta-analysis. This study will evaluate the association between total and specific types of nut consumption and the future risk of NCDs.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
1000000 (estimated)
First submitted
26 Sept 2025
Start date
1 Oct 2025
Primary completion date
30 Jun 2026
Lead sponsor
Institut Investigacio Sanitaria Pere Virgili
NCT number
NCT07205978

What you commit to

  • Study type: Observational
  • Planned participants: 1000000
  • From 1 Oct 2025 to the primary completion date, 30 Jun 2026
  • 2 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • The disease of interest at baseline

Age

  • Missing data on age, sex, and nut consumption.

Other

  • Prospective studies determining the consumption of nuts in combination with other food groups (e.g., seeds) or with other nut forms (e.g., butter or oil)
  • Participants with:
  • Extreme energy intakes (\<600 or \>3,500 kcal for women and \<800 or \>4,200 kcal for men)

Who the study is looking for

  • Prospective studies with:
  • Dietary data (consumption of nuts, both overall and/or by type) from semiquantitative food frequency questionnaires
  • Available data on at least two of the health outcomes of interest
  • More than 1,000 adult participants (aged 18 and over)
  • A minimum of five years of median follow-up

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Public Health, Section of Epidemiology
Coordinator of this site? Confirm its status
CopenhagenDenmarkUnknown status
Human Nutrition Unit - Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM).
Coordinator of this site? Confirm its status
ReusSpainUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.