NCT07207304Completed
Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes
Source: ClinicalTrials.gov · Last updated 23 Jun 2026
Brief summary (registry, in English)
Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes The goal of this clinical trial is to evaluate of the involvement of Neutrophil extracellular traps in the evolution of hepatocellular cancer. The main questions it aims to answer are: * How does the type of anesthesia used in hepatobiliary oncological surgery influence postoperative evolution and the immune response? * How does the type of anesthesia, TIVA versus inhalational influence the generation of neutrophil extracellular traps (NETs)? Researchers will compare the evolution of the patients assigned to 4 study groups depending on the anesthetic intervention performed. Participants will: * will be evaluated pre and postanesthesia, blood samples will be collected for analysis of the inflammatory response * will be followed up one year for establishing the outcome
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 153 (actual)
- First submitted
- 7 Jul 2025
- Start date
- 3 Feb 2022
- Primary completion date
- 23 Mar 2023
- Lead sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07207304
What you commit to
- Study type: Interventional
- Participants enrolled: 153
- From 3 Feb 2022 to the primary completion date, 23 Mar 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Undergoing emergency surgery
- Receiving chronic immunosuppressive therapy
- Having contraindications to any of the study medications
- Suffering from corticosteroid-dependent bronchial asthma
Other illness
- Barcelona-Clinic Liver Cancer stage C;
- Diagnosed with psychiatric disorders, such as: depression, bipolar disorder, schizophrenia, having autoimmune diseases
- Diagnosed with congenital or acquired coagulation disorders
Other
- Child-Pugh Class C
Who the study is looking for
- Diagnosed with: hepatocellular carcinoma, or hepatic metastases
- Scheduled for elective liver surgery:
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Regional Institute of Gastroenterology and Hepatology Octavian Fodor Coordinator of this site? Confirm its status | Cluj-Napoca | Romania | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.