NCT07208669Recruiting
Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes
Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes: the ACT-BP Pilot
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
The vast majority of the 36.2 million individuals admitted to U.S. hospitals are diagnosed with hypertension and experience an elevated blood pressure (BP) reading during hospitalization. There are no guidelines for managing asymptomatically elevated BPs in the inpatient setting, and growing observational evidence suggests that antihypertensive medication intensification increases harm. The proposed study tests whether a unit-based intervention (ACT-BP) can reduce antihypertensive medication intensification and provides information that is scientifically necessary for designing a cluster-randomized clinical trial that identifies the impact of intensification after experiencing an asymptomatically elevated BP on patient outcomes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 4 (estimated)
- First submitted
- 19 Sept 2025
- Start date
- 11 Nov 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Elizabeth Pfoh
- Diseases
- High blood pressure
- NCT number
- NCT07208669
What you commit to
- Study type: Interventional
- Planned participants: 4
- From 11 Nov 2025 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients experiencing hypertensive emergencies or cardiac symptoms
- Patients with active cardiovascular events, such as
- Stroke
- Non-ST-elevation
- Myocardial infarction
- End-stage renal disease
- Patients on dialysis
- Those with acute decompensated heart failure
- 3\. Patients on the unit for more than 10 days
- 4\. Patients transferred in after being in the intensive care unit (ICU)
- 5\. Pregnant and post-partum women
- 6\. Patients discharged within 24 hours of admission
- 7\. Patients whose systolic BP remains below 160 mmHg during hospitalization.
Other
- Patients less than 18
Who the study is looking for
- At the unit level: Medical units that do not typically care for patients requiring step-down care.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cleveland Clinic - Main Campus Coordinator of this site? Confirm its status | Cleveland | United States | Recruiting |
| Cleveland Clinic Hillcrest Coordinator of this site? Confirm its status | Mayfield Heights | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.