NCT07209098Recruiting
Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure
Broaden Accessibility of Breakthrough Treatment for Heart Failure: A Prospective, Propensity-Matched CED to Access the Impact of Cardiac Contractility Modulation Therapy (CCM)
Source: ClinicalTrials.gov · Last updated 24 Mar 2026
Brief summary (registry, in English)
The purpose of this prospective, multi-center, propensity-matched coverage with evidence development (CED) study is to assess the impact of cardiac contractility modulation (CCM) on mortality and heart failure hospitalizations in Medicare-eligible patients with heart failure who meet indications for CCM.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 4200 (estimated)
- First submitted
- 30 Sept 2025
- Start date
- Nov 2025
- Primary completion date
- Oct 2030
- Lead sponsor
- Impulse Dynamics
- Diseases
- Heart failure
- NCT number
- NCT07209098
What you commit to
- Study type: Observational
- Planned participants: 4200
- From Nov 2025 to the primary completion date, Oct 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subject has had a prior heart transplant
Other
- Subject with mechanical tricuspid valve.
- Subject has a left ventricular assist device (LVAD).
Who the study is looking for
- Continuous representation in the database in the year prior to index.
- Age 18 or older will be enrolled in either the treatment or control arm of the study.
- NYHA III heart failure,
- Not receiving CRT
- EF 25 - 45%, inclusive.
- Remain symptomatic despite at least 3 months of optimized guideline-directed medical therapy (GDMT) as determined by the heart team prior to CCM implantation.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Impulse Dynamics Coordinator of this site? Confirm its status | Marlton | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.