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NCT07209488Recruiting

Acquired Dyslexia Modeling and Treatment

Evidence-based Modeling for Acquired Dyslexia Treatments

Source: ClinicalTrials.gov · Last updated 6 May 2026

Brief summary (registry, in English)

This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
12 (estimated)
First submitted
2 Oct 2025
Start date
3 Dec 2025
Primary completion date
30 Sept 2026
Lead sponsor
Rutgers, The State University of New Jersey
Diseases
Stroke
NCT number
NCT07209488

What you commit to

  • Study type: Interventional
  • Planned participants: 12
  • From 3 Dec 2025 to the primary completion date, 30 Sept 2026
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
  • History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
  • Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.

Other

  • Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).

Who the study is looking for

  • Fluent in English as a first language pre-stroke by self report.
  • Normal or corrected-to-normal vision.
  • Normal or aided hearing.
  • Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
  • Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.

Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Johns Hopkins University School Of Medicine
Coordinator of this site? Confirm its status
BaltimoreUnited StatesRecruiting
Florida State University
Coordinator of this site? Confirm its status
TallahasseeUnited StatesRecruiting
Kessler Foundation
Coordinator of this site? Confirm its status
West OrangeUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.