NCT07211451Completed
Axillary Nodal Burden in HER2+ and TNBC
Low Axillary Nodal Metastasis Rates in Selected HER2-Positive and Triple-Negative Breast Cancer Patients: Toward De-escalation of Sentinel Lymph Node Biopsy
Source: ClinicalTrials.gov · Last updated 8 Oct 2025
Brief summary (registry, in English)
This study aimed to evaluated rates of pathologic axillary nodal metastasis in patients with with early-stage HER2-positive BC or TNBC who had clinically node-negative status on preoperative ultrasonography and underwent upfront breast-conserving surgery (BCS) with axillary surgery. In addition, this study aimed to identify subgroups in which SLNB omission may be feasible.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1571 (actual)
- First submitted
- 2 Oct 2025
- Start date
- 1 Jun 2025
- Primary completion date
- 31 Aug 2025
- Lead sponsor
- Gangnam Severance Hospital
- Diseases
- Triple-negative breast cancer
- NCT number
- NCT07211451
What you commit to
- Study type: Observational
- Participants enrolled: 1571
- From 1 Jun 2025 to the primary completion date, 31 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients who underwent mastectomy
- Absence of axillary nodal assessment on ultrasonography
- Patients who underwent mastectomy
- Patients who underwent mastectomy
Who the study is looking for
- HER2-positive breast cancer or TNBC
- Patients who received upfront breast conserving surgery with axillary surgery
- Patients who had a clinically axillary node negative disease
Age in the registry: 19 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gangnam Severance Hospital, Yonsei University College of Medicine Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.