NCT07213258Recruiting
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use disorder (MUD). The CHAMPION intervention combines two mHealth tools-PrEPAPP and CBT4CBT-to address both HIV prevention and MUD treatment needs in this population. The study's specific aims are: * To evaluate the feasibility and acceptability of the CHAMPION intervention based on treatment retention and engagement rates. * To examine the preliminary efficacy the CHAMPION intervention to improve PrEP adherence, as measured by dried blood spot (DBS) tests compared to the waitlist control group.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 24 Jan 2025
- Start date
- 24 Apr 2026
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- University of California, San Diego
- Diseases
- HIV
- NCT number
- NCT07213258
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 24 Apr 2026 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any condition that, in the principal investigator's judgment interferes with safe study participation or adherence to study procedures
Other
- Residing outside of San Diego or San Francisco County
- Not able/willing to complete virtual/remote visits
- Not willing to learn to self-collect dried blood spots using a finger stick
Who the study is looking for
- HIV-negative
- Cis-gender male
- Age 18-40 years old
- Mild or moderate MUD (by DSM-5 SCID criteria)
- Anal intercourse with one or more male partners in the past 6 months
- Started daily oral PrEP more than 30 days ago and self-reported not always taking PrEP as prescribed in the past 30 days (consistent with PrEP It! inclusion criteria)
- Willingness to participate in an mHealth study with a 6-month follow-up
- Residing in San Diego or San Francisco County
Age in the registry: 18 years to 40 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center on Substance Use and Health Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.