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NCT07220525Recruiting

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

Source: ClinicalTrials.gov · Last updated 2 Oct 2026

Brief summary (registry, in English)

Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
100 (estimated)
First submitted
22 Oct 2025
Start date
15 Dec 2025
Primary completion date
1 Jun 2027
Lead sponsor
University of California, San Francisco
NCT number
NCT07220525

What you commit to

  • Study type: Interventional
  • Planned participants: 100
  • From 15 Dec 2025 to the primary completion date, 1 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Are currently taking class 1 or 3 anti-arrhythmic medications

Other illness

  • Have a history of permanent AF or expected to have continuous AF throughout the study period
  • Have congenital heart disease

Other

  • Currently pregnant or trying to get pregnant
  • Ventricular pacing \>40%
  • Are unable to read or sign to provide informed consent

Who the study is looking for

  • Are age 21 years or older
  • Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health
  • Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period
  • Able and willing to provide written informed consent

Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UCSF Medical Center at Parnassus
Coordinator of this site? Confirm its status
San FranciscoUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.