NCT07220876Recruiting
Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial of the Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 165 (estimated)
- First submitted
- 22 Oct 2025
- Start date
- 7 Nov 2025
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- Avisi Technologies Inc.
- Diseases
- Glaucoma
- NCT number
- NCT07220876
What you commit to
- Study type: Interventional
- Planned participants: 165
- From 7 Nov 2025 to the primary completion date, 31 Oct 2027
- 14 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous intraocular surgery, with the exception of uncomplicated cataract surgery
- Previous glaucoma shunt/valve in the target quadrant
- Clinically significant inflammation or infection in the study eye within 30 days prior to the operative visit
Other illness
- History of corneal surgery, corneal opacities or corneal disease
- Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition
Other
- Angle closure glaucoma
- Congenital, neovascular or other secondary glaucomas
Who the study is looking for
- Open angle, pseudoexfoliative or pigmentary glaucoma
- IOP at preoperative visit of ≥ 20mmHg and ≤ 40mmHg
- Visual field mean deviation score of -3dB or worse
- Area of healthy, free and mobile conjunctiva in the target quadrant
- Shaffer angle grade ≥ 2 in the target quadrant
Age in the registry: 45 years to - · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas, Southwestern Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| Glaucoma Associates of Texas Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| Arizona Advanced Eye Research Coordinator of this site? Confirm its status | Glendale | United States | Recruiting |
| ICON Eye Care Coordinator of this site? Confirm its status | Grand Junction | United States | Recruiting |
| Houston Eye Associates Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| The Eye Centers of Racine & Kenosha Coordinator of this site? Confirm its status | Kenosha | United States | Recruiting |
| Advanced Vision Care Coordinator of this site? Confirm its status | Los Angeles | United States | Withdrawn |
| NYC Retina Coordinator of this site? Confirm its status | New York | United States | Recruiting |
| North Bay Eye Associates, Inc. Coordinator of this site? Confirm its status | Petaluma | United States | Recruiting |
| Wills Eye Hospital Coordinator of this site? Confirm its status | Philadelphia | United States | Withdrawn |
| Scheie Eye Institute Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Sacramento Eye Consultants Coordinator of this site? Confirm its status | Sacramento | United States | Recruiting |
| Lynette Venter Coordinator of this site? Confirm its status | Bloemfontein | South Africa | Recruiting |
| Pretoria Eye Institute Coordinator of this site? Confirm its status | Pretoria | South Africa | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.