NCT07223476Completed
Treatment Landscape and Real-World Dosing Patterns With CDK4/6 Inhibitors for Breast Cancer in Portugal
Treatment Landscape and Real-World Dosing Patterns With CDK4/6 Inhibitors for HR+/HER2- Advanced/Metastatic Breast Cancer in Portugal
Source: ClinicalTrials.gov · Last updated 31 Oct 2025
Brief summary (registry, in English)
Assess and characterize the real-world cyclin-dependent kinase 4/6 inhibitor (CDKI) use in advanced/metastatic breast cancer (a/mBC), evaluate treatment persistence, and quantify CDKI dose adjustments in Portugal. This study used secondary data from the IQVIA database that collects data from hospital drug consumption. The study included 16 public hospitals across Portugal, for which data on consumption of drugs used in hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) a/mBC treatment was available. Patient selection was based on a set of criteria considering all patients with treatments in the a/mBC setting with use of at least one CDKI from November 2018 to May 2023.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1926 (actual)
- First submitted
- 29 Oct 2025
- Start date
- Mar 2024
- Primary completion date
- Jul 2024
- Lead sponsor
- Novartis Pharmaceuticals
- NCT number
- NCT07223476
What you commit to
- Study type: Observational
- Participants enrolled: 1926
- From Mar 2024 to the primary completion date, Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Consumption patterns of target drugs that are not compatible with any known a/mBC treatment regimen.
Other illness
- Patients in early stages of breast cancer.
Who the study is looking for
- Male and female patients of all ages.
- Patients with at least one CDKI consumption from November 2018 to May 2023.
- Patients with consumptions in Gynecology and Oncology specialties.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Novartis Coordinator of this site? Confirm its status | East Hanover | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.