NCT07224191Recruiting
Hippocampal Oscillations During Exploration
Human Hippocampal Oscillations During Visuomotor Exploration
Source: ClinicalTrials.gov · Last updated 8 Jul 2026
Brief summary (registry, in English)
The objective of this study is to determine how visuomotor exploration relates to hippocampal activity along its long axis. The study will investigate the neurophysiological mechanisms in the hippocampus during (1) visual exploration in surgical patients using high-resolution iEEG, and (2) ambulatory exploration in patients implanted with RNS devices.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- First submitted
- 31 Oct 2025
- Start date
- 25 Feb 2026
- Primary completion date
- 8 Oct 2028
- Lead sponsor
- NYU Langone Health
- Diseases
- Epilepsy
- NCT number
- NCT07224191
What you commit to
- Study type: Interventional
- Planned participants: 56
- From 25 Feb 2026 to the primary completion date, 8 Oct 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Smoking tobacco, marijuana, recreational drugs or alcohol use within 1 week of cognitive testing
Other illness
- Any generalized tonic-clonic seizure within the last week
- All subjects:
Other
- RNS patients, Aim 2:
- Legally blind
- Unable to give informed consent
- Pregnancy
Who the study is looking for
- All subjects:
- Adults (18-70 years)
- Able to provide informed consent
- Aim 1: Surgical epilepsy patients' inclusion criteria
- Implanted hippocampal depth electrodes for Stage 1 epilepsy surgery
- MMSE\>=24
- Aim 2: RNS patients Inclusion criteria
- Implanted RNS device with at least one hippocampal depth electrode
- At least 5 months post-implantation to avoid the post-implant effect
- Have a relatively low number of seizures, defined as \<1 generalized tonic-clonic or other seizure with potential to fall or cause injury per month
- Able to walk and wear research equipment without assistance
- MMSE\>=24
- Aim 2: Healthy Control Inclusion criteria • Able to walk and wear research equipment without assistance
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NYU Langone Health Coordinator of this site? Confirm its status | New York | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.