NCT07224789Recruiting
Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA
Source: ClinicalTrials.gov · Last updated 7 Jul 2026
Brief summary (registry, in English)
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 3 Nov 2025
- Start date
- 15 Jan 2025
- Primary completion date
- 18 Jun 2028
- Lead sponsor
- City of Hope Medical Center
- Diseases
- Colorectal cancer
- NCT number
- NCT07224789
What you commit to
- Study type: Observational
- Planned participants: 600
- From 15 Jan 2025 to the primary completion date, 18 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of other active malignancies within the past 5 years
Other
- Poor sample quality or hemolysis
- Inability to provide informed consent
Who the study is looking for
- Adults (≥18 years old)
- Histologically confirmed colorectal cancer (Stage I-III)
- Availability of pre-treatment plasma samples
- Written informed consent provided
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| City of Hope Medical Center Coordinator of this site? Confirm its status | Duarte | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.