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NCT07225309Recruiting

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

Trial of Meaning Centered Psychotherapy for Mexican Patients With Advanced Cancer

Source: ClinicalTrials.gov · Last updated 3 Aug 2026

Brief summary (registry, in English)

The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
300 (estimated)
First submitted
15 Oct 2025
Start date
1 May 2026
Primary completion date
13 Apr 2029
Lead sponsor
Memorial Sloan Kettering Cancer Center
NCT number
NCT07225309

What you commit to

  • Study type: Interventional
  • Planned participants: 300
  • From 1 May 2026 to the primary completion date, 13 Apr 2029
  • 2 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior Treatment
    • Received psychological or psychiatric care at INCan in the last 3 months
    • In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation
    • Diagnosed with a serious psychiatric condition
    • Self-Report Criteria
  • Received psychological or psychiatric care outside of INCan in the last 3 months

Other

  • EMR Criteria
  • Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale
  • Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
    • Provider Eligibility Criteria:

Who the study is looking for

  • EMR Criteria
  • \- Documentation of Disease
  • Pathologically confirmed breast, prostate, colorectal, thyroid, cervix, uteri, or lung - solid tumor cancer (either most recent or new diagnosis)
    • Definition of Disease \[or Measurable Disease\]
  • Diagnosed with stages III or IV
    • Prior Treatment
  • Receiving ambulatory care at INCan
    • Self-Report Criteria
  • Age ≥ 18 years
  • Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
  • Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
  • Providing care (or services) to Mexican cancer patients at INCan
  • Has access to internet and an electronic device
  • Agrees to be audio-recorded
  • Age ≥ 18 years
  • Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
  • Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
  • Providing care (or services) to Mexican cancer patients at INCan
  • Has access to internet and an electronic device
  • Agrees to be audio-recorded

Criteria the registry did not label

  • Patient Eligibility Criteria:
  • A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener and suicide risk assessment.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Instituto Nacional de Cancerología (INCan)
Coordinator of this site? Confirm its status
Mexico CityMexicoNot yet recruiting
Memorial Sloan-Kettering Cancer Center
Coordinator of this site? Confirm its status
New YorkUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.