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NCT07226102Withdrawn

Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer

An E-Health Intervention for Fear of Progression in Women With Gynecologic or Breast Cancer

Source: ClinicalTrials.gov · Last updated 4 Feb 2026

Reason given: slow accrual

Brief summary (registry, in English)

This clinical trial tests feasibility, acceptability and how well a virtual mental health intervention, compared to enhanced usual care consisting of an educational intervention, works to address fear of progression for women with high risk or stage III-IV gynecologic or breast cancer. Worrying about cancer coming back or progression is natural for cancer patients. Many cancer patients face stress and uncertainty as they live longer and attend regular check-ups. A supportive program can help to develop skills to feel calmer and more resilient during uncertain times and better manage feelings of fear. The virtual mental health intervention may be a feasible, acceptable and effective may to address fear of progression for women with high risk or stage III-IV gynecologic or breast cancer.

Status (registry)
Withdrawn
Study type
Interventional
Enrollment
0 (actual)
First submitted
16 Oct 2025
Start date
16 Jul 2026
Primary completion date
16 Jul 2026
Lead sponsor
City of Hope Medical Center
NCT number
NCT07226102

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Enrolled in hospice
  • Major depression as assessed by patient health questionnaire (PHQ)-9
  • Non-English speaking
  • Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)

Who the study is looking for

  • Women with stage III or IV GYN (ovarian, endometrial, cervical, vulvar/vaginal) or breast cancer who are at least 2 months from initial diagnosis
  • Women with high-risk disease e.g., carcinosarcoma; ovarian cancer stage II or grade III histology; endometrioid endometrial cancer stage II or III; grade III with LVI or deep invasion; serous, clear cell or undifferentiated histologies; triple negative breast cancer
  • Score ≥ 34 on the Fear of Progression Short-Form, indicating dysfunctional levels
  • Age 18 or older; able to read and understand English
  • Patients in remission or with progressive disease

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (12)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
City of Hope at ArcadiaArcadiaUnited StatesUnknown status
City of Hope Medical CenterDuarteUnited StatesUnknown status
City of Hope at Irvine LennarIrvineUnited StatesUnknown status
City of Hope Antelope ValleyLancasterUnited StatesUnknown status
City of Hope at Long Beach WorshamLong BeachUnited StatesUnknown status
City of Hope at Long Beach ElmLong BeachUnited StatesUnknown status
City of Hope Mission HillsMission HillsUnited StatesUnknown status
City of Hope - Santa ClaritaSanta ClaritaUnited StatesUnknown status
City of Hope at Simi ValleySimi ValleyUnited StatesUnknown status
City of Hope at Thousand OaksThousand OaksUnited StatesUnknown status
City of Hope South BayTorranceUnited StatesUnknown status
City of Hope UplandUplandUnited StatesUnknown status

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This page is information, not medical advice. Discuss any trial with your doctor.