NCT07226336CompletedPhase 2
Dietary Interventions to Reduce Ultra-Processed Food Intake
Testing a Dissonance-Based Intervention to Reduce Ultra-Processed Food Consumption Via Activism Against the Food Industry
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
The DISRUPT clinical trial will test two different 2-month programs to help adults with overweight/obesity (N=60) reduce their intake of ultra-processed foods (UPFs). Participants will be randomly assigned to receive standard dietary change strategies, cognitive dissonance strategies that engage them in activism against the UPF industry, or both. All participants will attend an introductory educational workshop about UPFs. If they are assigned to receive one or more of these strategies, they will attend weekly group sessions with the relevant intervention content for 7 more weeks. Groups will be held virtually.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 59 (actual)
- First submitted
- 31 Oct 2025
- Start date
- 10 Feb 2026
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Oregon Research Institute
- Diseases
- Obesity
- NCT number
- NCT07226336
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 59
- From 10 Feb 2026 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Are using medications known to influence eating behavior and/or weight (e.g., semaglutide)
- Currently using insulin
Other illness
- History of bariatric surgery
Other
- Have ever been diagnosed with anorexia nervosa or bulimia nervosa
- Current pregnancy or planning to become pregnant during the study period
Who the study is looking for
- Ages 18-70 years old
- BMI \>25 and \<50 kg/m2
- Wish to reduce their UPF intake
- Consume at least 2 UPF items per day and at least 4 distinct UPF items per week
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Oregon Research Institute Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
Related publications
- A cognitive dissonance-based intervention to reduce ultra-processed food intake: Protocol for a pilot randomized controlled trial.Contemp Clin Trials · 2026 · PMID 42031230
This page is information, not medical advice. Discuss any trial with your doctor.