NCT07227961Recruiting
Activation Sarcoma: PROMIS and Mobility Evaluation in Sarcoma Patients
Patient-Reported Outcomes and Smartphone-Derived Mobility After Bone and Soft Tissue Sarcoma Surgery: A Multicentre Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
Sarcoma is a rare form of bone and soft tissue cancer, making up about 1% of all adult cancers. Management typically involves radiation therapy, chemotherapy, and surgical resection. Surgery is central to the treatment of bone and soft tissue sarcoma, yet post-surgical recovery is difficult to measure because of disease rarity, multiple different tumor types, and treatment variation. Therefore, the overall goal of the study is to use patient reported outcome measures and mobility data to define recovery trajectories in sarcoma patients undergoing surgery, and to evaluate a novel smartphone application (app) entailed Activation Health for collecting these data. Participants will download the Activation Health app on their smartphone. A demographics survey and multiple patient reported outcome measures will be administered remotely through the Activation Health app. Surveys will be completed preoperatively and at 6 weeks, 12 weeks, 6 months 12 months, 16 months, 20 months, and 24 months postoperatively. Additionally, the app will passively track mobility metrics such as daily step count, stairs climbed, and gait parameters throughout the study period. At the end of study participation, an additional surveys will be administered assess participant phone use habits and app function.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 4 Nov 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 30 Jun 2030
- Lead sponsor
- University of Calgary
- Diseases
- Sarcoma
- NCT number
- NCT07227961
What you commit to
- Study type: Observational
- Planned participants: 800
- From 1 Jul 2025 to the primary completion date, 30 Jun 2030
- 4 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Metastatic bone tumor
- Diagnosis of atypical lipomatous tumor
- Diagnosis of dermatofibrosarcoma protuberans
- Currently pregnant or planning pregnancy within 6 months
- Unwilling or unable to attend follow-up evaluations
- Cognitive or communication barriers that impede completion of questionnaires
Who the study is looking for
- Age ≥ 18 years
- Diagnosis of bone sarcoma, soft tissue sarcoma, or giant cell tumor of bone
- Tumors located in the pelvis, lower extremities, or upper extremities
- Primary or recurrent disease
- Undergoing operative tumor resection, including limb salvage surgery and amputation
- Has an iPhone or Android smartphone
- Speaks English
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Foothills Medical Centre, Arthur J Child Comprehensive Cancer Centre, University of Calgary Coordinator of this site? Confirm its status | Calgary | Canada | Recruiting |
| Mount Sinai Hospital, University of Toronto Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Mayo Clinic Coordinator of this site? Confirm its status | Phoenix | United States | Not yet recruiting |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.