NCT07228429Recruiting
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Quantification of Calcinosis Cutis Disease Burden in Patients With Systemic Sclerosis Using Computed Tomography Images
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 56 (estimated)
- First submitted
- 12 Nov 2025
- Start date
- 14 Oct 2025
- Primary completion date
- May 2027
- Lead sponsor
- Yale University
- Diseases
- Systemic sclerosis (scleroderma)
- NCT number
- NCT07228429
What you commit to
- Study type: Observational
- Planned participants: 56
- From 14 Oct 2025 to the primary completion date, May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Unable to provide informed consent
- Currently pregnant or nursing
- Patients with a calcinosis ROI \>6cm
Who the study is looking for
- Scleroderma/systemic sclerosis patient with diagnosed calcinosis cutis who will be clinically treated with STS as they would in clinical SOC care
- Must be ≥ 18 years old and meet the 2013 American College of Rheumatology criteria for the diagnosis of systemic sclerosis (diffuse or limited)
- Receiving clinical care at Yale clinics
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yale Scleroderma Program Coordinator of this site? Confirm its status | New Haven | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.