NCT07230873Completed
The Impact of Stationary Combined Exercise on Adiponectin and Hs-CRP Levels in Overweight Women
The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive Protein Levels in Overweight Women
Source: ClinicalTrials.gov · Last updated 19 Nov 2025
Brief summary (registry, in English)
This study looked at whether a specific exercise program can improve inflammatory markers in overweight young women. We tested an eight-week, circuit-style exercise program that combines aerobic and resistance activities (e.g., sit-ups, step jumps, push-ups, jump rope, jumping jacks, medicine-ball lifts). Participants exercised four times per week at a moderate-to-high intensity, with a warm-up and cool-down at each session. Twenty-two women (ages 20-30 years; BMI 25-31 kg/m²) were randomly assigned to one of two groups: (1) the exercise group completed the training program; (2) the control group continued usual daily activities without a structured program. Before starting and 48 hours after finishing the program, we took fasting blood samples to measure two markers: adiponectin (a hormone made by fat tissue that supports healthy metabolism and has anti-inflammatory effects) and high-sensitivity C-reactive protein (hs-CRP) (a blood marker of inflammation and cardiovascular risk). The main outcomes were the changes in adiponectin and hs-CRP from before to after the 8-week period. We also recorded weight, body mass index (BMI), body fat percentage, and fitness (VO₂max). The study was conducted at the Exercise Physiology Laboratory, College of Physical Education and Health, Chongqing College of International Business and Economics (Chongqing, China). The research ethics committee approved the protocol, and all participants provided written informed consent. Recruitment and data collection are complete. Findings suggest that this circuit-based exercise program can increase adiponectin and lower hs-CRP, alongside improvements in body composition, in overweight young women.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 13 Sept 2025
- Start date
- 20 Jan 2024
- Primary completion date
- 10 Apr 2024
- Lead sponsor
- Xianjie Zheng
- Diseases
- Obesity
- NCT number
- NCT07230873
What you commit to
- Study type: Interventional
- Participants enrolled: 22
- From 20 Jan 2024 to the primary completion date, 10 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of cardiovascular disease, hypertension, or diabetes Current smoking or tobacco use Current use of medications or supplements that affect metabolism or inflammatory markers Pregnancy or breastfeeding Contraindications to moderate-to-high intensity exercise on screening Participation in regular vigorous exercise training within the past 6 months Inability or unwillingness to comply with study procedures (e.g., missing \>2 consecutive training sessions)
Who the study is looking for
- Female sex Age 20 to 30 years BMI 25 to 31 kg/m² Body weight 63 to 87 kg Generally healthy, without diagnosed chronic illness Willing and able to provide written informed consent Willing to refrain from vigorous physical activity for 48 hours before blood sampling Able to attend 4 supervised training sessions per week for 8 weeks (if assigned to intervention)
Age in the registry: 20 years to 30 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| College of Physical Education and Health Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.