NCT07231900Not yet recruitingPhase 2/3
Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients
Source: ClinicalTrials.gov · Last updated 17 Nov 2025
Brief summary (registry, in English)
The study is designed to diminish intra-dialytic hypertension in chrnic hemodialysis patients suffering from metabolic acidosis (low bicarbonate levels). The intervention is a tab of 500 mg sodium bicarbonate twice a day for one month, vs. placebo.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 14 Nov 2025
- Start date
- 10 Nov 2025
- Primary completion date
- 1 Dec 2027
- Lead sponsor
- Assaf-Harofeh Medical Center
- Diseases
- High blood pressure
- NCT number
- NCT07231900
What you commit to
- Study type: Interventional · Phase 2/3
- Planned participants: 40
- From 10 Nov 2025 to the primary completion date, 1 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- planned for kidney transplant in the following 3 month.
- low compliece to medical therapy
Other illness
- congestive heart failure (NYHA 3-4)
Age
- age under 18,
Other
- pregnancy
- unable to sign informed concent
- hospitalization for acute MI or CHF in the past 3 months.
- regular pre-dialysis tests with bicarbonate \> 24 in the past 3 months
Who the study is looking for
- Chronic hemodialysis patient \> 3 months
- 3 dialysis per week, KTV\>1.2
- capable of informed concent.
- rise in blood pressure during hemodialysis \> 10 mm Hg, for at least 50% of dialysis sessions in the month prior to inclusion.
- Normal volume status, by clinical physician assessment + bioimpedance
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shamir Medical Center Coordinator of this site? Confirm its status | Tsrifin | Israel | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.