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NCT07232485Recruiting

Retinal Imaging for Systemic Inflammation in Endometriosis

Retinal Imaging for the Assessment of Systemic Inflammation in Endometriosis

Source: ClinicalTrials.gov · Last updated 21 Oct 2026

Brief summary (registry, in English)

There is increasing evidence that examining our eyes can tell us a lot of information about our health, and systemic diseases. Our plan is to compare the images taken of the back of eyes of women who have endometriosis with those of women who don't. We want to study what eyes can reveal about endometriosis by analyzing the retinal images from a simple noninvasive eye scan, that is already being routinely used to provide immediate clinical information in other groups of patients (eg. diabetic eye screening).

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
1 Sept 2025
Start date
3 Sept 2025
Primary completion date
Aug 2029
Lead sponsor
University of Edinburgh
NCT number
NCT07232485

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 3 Sept 2025 to the primary completion date, Aug 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Participants with a previous surgical or imaging diagnosis of endometriosis
    • The subject has donated blood (450 ml) within the last 4 weeks
    • Known reproductive tract malignancy
    • Ocular Diseases:
    • Subjects with clinically diagnosed glaucoma, optic neuropathy, optic neuritis, cataracts, or other conditions that affect the ocular structures.
    • Subjects with age-related macular degeneration, retinal vascular diseases, or other retinal disorders.
    • Subjects with any other ocular conditions that may influence the retinal or optic nerve structure.
    • Refractive Errors:
    • Subjects with high myopia (\>6 diopters) or high hyperopia (\>3 diopters).
    • Subjects with significant astigmatism (\>2 dioptres) or other refractive errors.
    • Ocular Surgery History: Subjects with a history of ocular surgery, particularly involving the lens, cornea, retina, or optic nerve (e.g., laser vision correction, retinal surgeries, etc.).
    • Subjects with significant ocular trauma, corneal abnormalities, or active ocular infections that may interfere with OCT imaging.
    • Subjects with diabetes mellitus

Age

  • Healthy volunteers
    • The subject has donated blood (450 ml) within the last 4 weeks
    • Known reproductive tract malignancy
    • A history of symptoms suggestive of endometriosis or chronic pelvic pain
    • Ocular Diseases:
    • Subjects with clinically diagnosed glaucoma, optic neuropathy, optic neuritis, cataracts, or other conditions that affect the ocular structures.
    • Subjects with age-related macular degeneration, retinal vascular diseases, or other retinal disorders.
    • Subjects with any other ocular conditions that may influence the retinal or optic nerve structure.
    • Refractive Errors:
    • Subjects with high myopia (\>-6 dioptres) or high hyperopia (\>+6 dioptres).
    • Subjects with significant astigmatism (\>2 dioptres) or other refractive errors.
    • Ocular Surgery History: Subjects with a history of ocular surgery, particularly involving the lens, cornea, retina, or optic nerve (e.g., laser vision correction, retinal surgeries, etc.).
    • Subjects with significant ocular trauma, corneal abnormalities, or active ocular infections that may interfere with OCT imaging.
    • Subjects with diabetes mellitus

Who the study is looking for

  • Participants with a previous surgical or imaging diagnosis of endometriosis
    • Pre-menopausal women and those assigned female at birth
    • Aged 18 years and over
    • A past surgical or imaging diagnosis of endometriosis within the last 5 years from date of consent
    • Ability to understand and willingness to sign the informed consent form
  • Healthy volunteers
    • Women and those assigned female at birth
    • Aged 18 years and over
    • No history of endometriosis or chronic pelvic pain
    • Ability to understand and willingness to sign the informed consent form

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Edinburgh
Coordinator of this site? Confirm its status		EdinburghUnited KingdomRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.