NCT07232927Completed
Evaluation of Hemostatic Agents in Partial Nephrectomy
Evaluation of Hemostatic Agents in Partial Nephrectomy: A Prospective Randomized Trial
Source: ClinicalTrials.gov · Last updated 18 Nov 2025
Brief summary (registry, in English)
This prospective randomized study aims to evaluate the effect of adjunctive hemostatic agents (FloSeal® and Surgicel®) on perioperative outcomes in patients undergoing partial nephrectomy for localized renal tumors. A total of 150 patients were randomized into three groups: standard parenchymal suturing (Group A), suturing with FloSeal® (Group B), and suturing with Surgicel® (Group C). The study primarily investigates whether hemostatic agents reduce postoperative hemorrhage, urinary leakage, and positive surgical margin rates. Secondary outcomes include renal function change, operative and ischemia times, estimated blood loss, and hospital stay. All surgeries were performed by a single experienced surgeon at Ankara University Urology Department between January 2023 and December 2024.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 150 (actual)
- First submitted
- 13 Nov 2025
- Start date
- 2 Jan 2023
- Primary completion date
- 1 Dec 2024
- Lead sponsor
- Ankara University
- Diseases
- Kidney cancer
- NCT number
- NCT07232927
What you commit to
- Study type: Interventional
- Participants enrolled: 150
- From 2 Jan 2023 to the primary completion date, 1 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of previous renal surgery on the same kidney.
Other illness
- Evidence of metastatic disease or locally advanced (≥T2) renal tumors.
- Coagulopathy, bleeding disorders, or ongoing anticoagulant therapy that cannot be discontinued.
- Active urinary tract infection or systemic infection.
- Known allergy or hypersensitivity to gelatin or oxidized cellulose components.
Other
- Patients with solitary kidney or bilateral renal tumors.
- Patients who decline participation or withdraw consent.
- Incomplete perioperative data or loss to follow-up.
Who the study is looking for
- Patients aged 18 years or older.
- Diagnosed with localized renal mass (clinical stage T1a-T1b) suitable for partial nephrectomy.
- Adequate preoperative renal function to undergo surgery.
- Signed informed consent obtained prior to study enrollment.
- Undergoing open, laparoscopic, or robotic partial nephrectomy performed by the same experienced surgeon.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ankara University Faculty of Medicine, Department of Urology Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.