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NCT07235423Not yet recruiting

Predictors of Post-Thrombectomy Cognitive Impairment in Acute Ischemic Stroke Patients

Predictors of Post-Thrombectomy Cognitive Impairment in Acute Ischemic Stroke Patients : a Prospective Cohort Study

Source: ClinicalTrials.gov · Last updated 19 Nov 2025

Brief summary (registry, in English)

This prospective cohort study investigates predictors of post-stroke cognitive impairment (PSCI) in patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke due to large vessel occlusion. Adult patients with successful reperfusion (mTICI 2b-3) will be followed at 3 and 6 months to assess cognition, functional recovery, and depression. Predictors across clinical, procedural, radiological, and laboratory domains will be analyzed. The study aims to identify risk factors for PSCI, estimate its prevalence, and evaluate its impact on outcomes.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
120 (estimated)
First submitted
19 Sept 2025
Start date
1 Dec 2025
Primary completion date
30 Dec 2027
Lead sponsor
Assiut University
Diseases
Stroke
NCT number
NCT07235423

What you commit to

  • Study type: Observational
  • Planned participants: 120
  • From 1 Dec 2025 to the primary completion date, 30 Dec 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Pre-existing dementia ( using Arabic version of the Short Form of the Informant Questionnaire on Cognitive Decline in the Elderly).

Other

  • Severe aphasia/coma interfering with cognitive assessment.
  • Non-ischemic etiology.
  • Death within 72 hours.
  • Refusal to participate in the study.

Who the study is looking for

  • Adults (≥18 years).
  • Acute ischemic stroke due to anterior circulation LVO confirmed by imaging undergoing EVT per guidelines.
  • Successful reperfusion (mTICI 2b-3)
  • Able to provide consent.

Age in the registry: 18 years to - · Sex: All

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.