NCT07235839Active, not recruiting
The Impact of an Advance Care Planning Game on Life-Sustaining Treatment Preferences, Depression, and Hope in Older Adults With Stroke
Source: ClinicalTrials.gov · Last updated 4 Feb 2026
Brief summary (registry, in English)
Stroke is the world's third leading cause of death and a major source of disability, with high rates of recurrence and mortality that often limit patients' ability to express their values and treatment preferences. This highlights the importance of Advance Care Planning (ACP) after stroke. This randomized controlled trial examined the effects of an ACP block-based game on life-sustaining treatment preferences, depression, and hope among adults aged 65-100 with subacute stroke in a regional teaching hospital. The Life Support Preferences Questionnaire (LSPQ) served as the primary outcome to assess preference changes immediately after the intervention and at four weeks, while the Hospital Anxiety and Depression Scale (HADS) and the Herth Hope Index (HHI) were secondary measures. The intervention used the "LOHAS Journey" ACP game, which applies travel-themed scenarios, blocks to express medical choices, hope-enhancing elements, and companion cards emphasizing personal resources and potential surrogate decision-makers, while also encouraging warm emotional expression. Generalized Estimating Equations (GEE) were used to analyze repeated measures and time-by-group effects. If effective, this ACP game may support broader clinical adoption of structured discussions on life-sustaining treatment preferences for older stroke patients.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 72 (estimated)
- First submitted
- 14 Nov 2025
- Start date
- 29 Jan 2026
- Primary completion date
- 31 May 2026
- Lead sponsor
- Lotung Poh-Ai Hospital
- Diseases
- Stroke
- NCT number
- NCT07235839
What you commit to
- Study type: Interventional
- Planned participants: 72
- From 29 Jan 2026 to the primary completion date, 31 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals diagnosed with chronic psychiatric disorders such as major depression, mania, or bipolar disorder.
- Older adults diagnosed with moderate to severe dementia.
Who the study is looking for
- Older adults aged 65-100 years.
- Diagnosed with ischemic or hemorrhagic stroke confirmed by computer tomography (CT) or magnetic resonance imaging (MRI), and in the subacute stage 1-6 months after stroke onset.
- A National Institute of Health Stroke Scale (NIHSS) score ≤ 15, indicating mild to moderate stroke severity.
- Clear consciousness and able to communicate in Mandarin or Taiwanese.
Age in the registry: 65 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lotong PohAi Hospital Coordinator of this site? Confirm its status | Yilan | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.