NCT07236840Recruiting
Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors
Source: ClinicalTrials.gov · Last updated 24 Feb 2026
Brief summary (registry, in English)
The goal of this observational study is to evaluate the feasibility and accuracy of a self-administered remote neurological examination using the "Iskhaa" mobile application in patients with brain tumors aged above 5 years who are able to follow app-based instructions. The main questions it aims to answer are: 1. Development of a mobile application equipped with symptom assessment and recording videos as patients perform specific neurological tasks. 2. Development and validation of the AI model to detect functional changes and predict subsequent neurological deterioration. Participants will: 1. Use the Iskhaa mobile application to perform guided self-neurological examinations following pre-recorded video instructions. 2. Complete EORTC QLQ-C30 and BN20 questionnaires for quality of life assessment. 3. Record and upload videos (e.g., speech, walking, limb movements) using their mobile camera for analysis. 4. In Phase 1 (onsite), 100 participants will use the app under supervision to ensure usability and accuracy. 5. In Phase 2 (offsite), 500 participants will use the app independently at home for monthly self-assessments, with reminders and follow-up support. 6. Continue routine clinic visits every 3-6 months and imaging every 6-12 months as per standard clinical care. The study will compare app-recorded data with physician assessments to determine agreement and validity of remote neurological monitoring using artificial intelligence analysis.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 14 Nov 2025
- Start date
- 20 Feb 2026
- Primary completion date
- 1 Nov 2027
- Lead sponsor
- Tata Memorial Centre
- Diseases
- Childhood cancers
- NCT number
- NCT07236840
What you commit to
- Study type: Observational
- Planned participants: 600
- From 20 Feb 2026 to the primary completion date, 1 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient with severe cognitive or psychiatric issues causing difficulty in using the app or follow instructions.
- Terminal illness with expected life expectancy (\<6 months).
Other
- Patient or caregiver is not reliable to follow instructions or use the mobile application.
- Karnofsky Performance Status (KPS) or Lansky Performance Status LPS) \<50.
Who the study is looking for
- Diagnosis of brain tumors (histopathology/ radiology).
- Age \> 5 years
- Patient or caregiver have access to an android smart phone and is able to install the mobile application.
- Expected survival more than 6 months during study accrual.
- Signing patient consent or parent consent/ child assent form (as appropriate).
Age in the registry: 5 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tata Memorial Centre Coordinator of this site? Confirm its status | Mumbai | India | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.