NCT07238049Enrolling by invitation
REAl World Dementia OUTcomes: Observational Study
READ-OUT - REAl World Dementia OUTcomes: Observational Study
Source: ClinicalTrials.gov · Last updated 20 Nov 2025
Brief summary (registry, in English)
READ-OUT observational study will investigate blood-based biomarkers for dementia in real-world clinical settings. This 3-year observational study will include 3165 people, males or females aged 45 years or older, with cognitive impairment of any severity. Participants provide blood samples and complete questionnaires about quality of life and healthcare use, with some having additional follow-ups at 2 weeks and 1 year. The study will assess reliability and accuracy of blood tests in diagnosing dementia.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 3165 (estimated)
- First submitted
- 1 Sept 2025
- Start date
- 1 Nov 2024
- Primary completion date
- 31 Oct 2029
- Lead sponsor
- University of Oxford
- Diseases
- Alzheimer disease
- NCT number
- NCT07238049
What you commit to
- Study type: Observational
- Planned participants: 3165
- From 1 Nov 2024 to the primary completion date, 31 Oct 2029
- 27 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- The participant may not enter the study if ANY of the following apply:
- Lack of venous access
- Unwilling to consent to NHS data linkage or in Northern Ireland, unwilling to allow long term follow up by access to electronic NHS records.
Who the study is looking for
- The participant may enter the study if ALL of the following apply:
- Willing and able to give informed consent for participation in the study (translation needs for study information and forms for non-English speakers will be defined locally) OR Adults who otherwise lack the capacity to consent but for whom advice regarding participation has been obtained via a consultee using the personal or nominated consultee process
- Male or Female, aged 45 years and above
- Referred or referable with cognitive or behavioural symptoms and/or diagnosed with a cognition related disorder; including those with subjective cognitive impairment and functional disorders.
Age in the registry: 45 years to - · Sex: All · Does not accept healthy volunteers
Sites (27)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Betsi Cadwaladr University Health Board Coordinator of this site? Confirm its status | Bangor | United Kingdom | Unknown status |
| ReMind UK Coordinator of this site? Confirm its status | Bath | United Kingdom | Unknown status |
| Belfast Health & Social Care Trust Coordinator of this site? Confirm its status | Belfast | United Kingdom | Unknown status |
| Dorset Healthcare University NHS Foundation Trust Coordinator of this site? Confirm its status | Bournemouth | United Kingdom | Unknown status |
| Berkshire Healthcare NHS Foundation Trust Coordinator of this site? Confirm its status | Bracknell | United Kingdom | Unknown status |
| Bradford District Care NHS Foundation Trust Coordinator of this site? Confirm its status | Bradford | United Kingdom | Unknown status |
| North Bristol NHS Trust Coordinator of this site? Confirm its status | Bristol | United Kingdom | Unknown status |
| Cambridgeshire and Peterborough NHS Foundation Trust Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Unknown status |
| Devon Partnership NHS Trust Coordinator of this site? Confirm its status | Exeter | United Kingdom | Unknown status |
| East London NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| South London and Maudsley (SLaM) Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| West London NHS Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Barts Health NHS Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| St. George's Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Greater Manchester Mental Health Foundation Trust Coordinator of this site? Confirm its status | Manchester | United Kingdom | Unknown status |
| Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust Coordinator of this site? Confirm its status | Newcastle upon Tyne | United Kingdom | Unknown status |
| Aneurin Bevan University Health Board Coordinator of this site? Confirm its status | Newport | United Kingdom | Unknown status |
| Nottingham University Hospitals NHS Trust Coordinator of this site? Confirm its status | Nottingham | United Kingdom | Unknown status |
| Oxford Health NHS Trust Coordinator of this site? Confirm its status | Oxford | United Kingdom | Unknown status |
| Lancashire & South Cumbria NHS Foundation Trust Coordinator of this site? Confirm its status | Preston | United Kingdom | Unknown status |
| Surrey and Borders Partnership NHS Foundation Trust Coordinator of this site? Confirm its status | Redhill | United Kingdom | Unknown status |
| Sheffield Health and Social care NHS Foundation Trust Coordinator of this site? Confirm its status | Sheffield | United Kingdom | Unknown status |
| Sheffield Teaching Hospital Coordinator of this site? Confirm its status | Sheffield | United Kingdom | Unknown status |
| University Hospital Southampton Coordinator of this site? Confirm its status | Southampton | United Kingdom | Unknown status |
| Hampshire and Isle of Wight NHS Foundation Trust Coordinator of this site? Confirm its status | Southampton | United Kingdom | Unknown status |
| Midlands Partnership University NHS Foundation Trust Coordinator of this site? Confirm its status | Stafford | United Kingdom | Unknown status |
| Sussex Partnership NHS Foundation Trust Coordinator of this site? Confirm its status | Worthing | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.