NCT07238426Enrolling by invitation
ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey
ATTRACT-52: Advancing TTR Testing and Risk-Based Amyloidosis Cardiac Screening in Primary Care - The Ordu Pilot Study
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
Cardiac amyloidosis is a progressive infiltrative cardiomyopathy, most commonly related to transthyretin (ATTR) misfolding. Although considered rare, emerging data suggest higher prevalence in specific regions, including the Black Sea area of Turkey. Early recognition improves outcomes. ATTRACT-52 is a prospective, observational, non-interventional screening study in primary care (family medicine centers) across Ordu province. Adults ≥65 years with cardiac or musculoskeletal "red flags" will be screened; those meeting high-suspicion criteria will undergo NT-proBNP/BNP testing at the primary care level to aid risk stratification prior to referral for confirmatory diagnostics.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 15 Nov 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Kotyora Family Medicine Health Management and Education Association
- Diseases
- Amyloidosis
- NCT number
- NCT07238426
What you commit to
- Study type: Observational
- Planned participants: 800
- From 1 Dec 2025 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent participation in an interventional trial
Lab values
- Severe renal impairment (eGFR \<30 mL/min/1.73m²)
Other
- Known systemic AL amyloidosis
- Inability to provide consent
Who the study is looking for
- Age ≥65 years
- Registered patient in participating Family Medicine Centers (Ordu province)
- Cardiac history including at least one of: heart failure (I50), aortic stenosis (I35.0), cardiomyopathy (I42), atrioventricular block (I44), or atrial fibrillation (I48)
- Echocardiographic interventricular septal thickness ≥12 mm with preserved LVEF (≥50%), when available
- Ability to provide verbal or written consent
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ordu University Faculty of Medicine, Department of Cardiology Coordinator of this site? Confirm its status | Ordu | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.