NCT07240220Not yet recruiting
The Mother-Daughter Project: Merck-4
The Mother-Daughter Project: Inclusion of Difficult-to-reach Kenyan Families, and Studies of Factors Influencing the Immune Response to HPV Vaccination (Merck-4)
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
This project serves to continue a community-based initiative, known as the Kenya Mother-Daughter Cervical Cancer Eradication Project, or the Mother-Daughter Project (MDP), in the Webuye region of Western Kenya. The MDP project, since its initiation in 2018, has sought to develop a framework for the eradication of cervical cancer through effective screening of adult women and through the vaccination of female children. This project specifically aims to collect additional data on the ability for HR-HPV testing to detect premalignant lesions of the cervix, especially in HIV-infected women, to investigate and identify barriers leading to non-participation in previous MDP efforts, and to examine factors associated with the immune response to HPV vaccination among rural Kenyan girls.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 2500 (estimated)
- First submitted
- 16 Nov 2025
- Start date
- 1 Feb 2026
- Primary completion date
- 1 Aug 2028
- Lead sponsor
- Indiana University
- Diseases
- Cervical cancer, Childhood cancers
- NCT number
- NCT07240220
What you commit to
- Study type: Interventional
- Planned participants: 2500
- From 1 Feb 2026 to the primary completion date, 1 Aug 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- girls who are not willing or unable to return for the second HPV vaccine dose
Other
- pregnant
- Kenyan Girls
Who the study is looking for
- ages 25 through 49 years
- able/willing to sign informed consent
- willing to participate in the community meetings
- ages 9 through 14 years
- have mother that is able/willing to sign informed consent for vaccination
- can return for the second HPV vaccine dose in 6 - 12 months
Criteria the registry did not label
- Kenyan Adult Women
Age in the registry: 9 years to 49 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Moi University Coordinator of this site? Confirm its status | Eldoret | Kenya | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.