NCT07241117RecruitingPhase 4
CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing patterns, and offer educational tools for patients and providers. The investigators will roll out these resources in stages across clinics. The study will measure how well the program helps clinicians prescribe SMART therapy and whether it reduces asthma exacerbations in patients.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 2000 (estimated)
- First submitted
- 7 Nov 2025
- Start date
- 6 Jan 2026
- Primary completion date
- 15 Nov 2027
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Asthma
- NCT number
- NCT07241117
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 2000
- From 6 Jan 2026 to the primary completion date, 15 Nov 2027
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- The study population can be viewed from the cluster (clinic), clinician, staff, or patient level.
- At the cluster (clinic) level: To be eligible to participate in this study, a cluster (clinic) must meet all the following criteria:
- (1) Clinics within participating health systems (Affinia Healthcare and Family Care Health Centers) will be considered eligible if they provided care to ≥100 patients aged ≥12 years with asthma (ICD-10-CM: J45.xx) during the calendar year preceding implementation (2024).
- At the clinician level:
- Clinicians will be considered eligible if they:
- are physicians, nurse practitioners, or physician assistants;
- are actively employed at a participating clinic during the implementation period; and
- provided care to ≥10 patients aged ≥12 years with asthma (ICD-10-CM: J45.xx) during the 12 months preceding implementation.
- At the staff level:
- Staff will be considered eligible if they:
- are actively employed at a participating clinic during the implementation period; and
- directly support clinical care delivery for patients aged ≥12 years with asthma.
- At the patient level:
- Patients will be considered eligible if they:
- are aged ≥12 years;
- received care at a participating clinic during the implementation period; and (3) meet the study-defined definition of moderate-to-severe asthma based on diagnosis codes, medication use, and/or exacerbation history as defined in the study protocol.
Age in the registry: 12 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Affinia healthcare, 3396 Pershall Road, Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Affinia healthcare, 4414 North Florissant Avenue Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Washington University in St. Louis, School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Affinia healthcare, 2220 Lemp Ave Coordinator of this site? Confirm its status | St Louis | United States | Not yet recruiting |
| Family Care Heath Center, 4352 Manchester Ave Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Family Care Heath Center, 401 Holly Hills Ave Coordinator of this site? Confirm its status | St Louis | United States | Not yet recruiting |
| Affinia healthcare, 1717 Biddle Street Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.