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NCT07241117RecruitingPhase 4

CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma

Source: ClinicalTrials.gov · Last updated 10 Sept 2026

Brief summary (registry, in English)

Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Single Maintenance and Reliever Therapy). The investigators will provide training and resources to clinicians, give feedback on prescribing patterns, and offer educational tools for patients and providers. The investigators will roll out these resources in stages across clinics. The study will measure how well the program helps clinicians prescribe SMART therapy and whether it reduces asthma exacerbations in patients.

Status (registry)
Recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
2000 (estimated)
First submitted
7 Nov 2025
Start date
6 Jan 2026
Primary completion date
15 Nov 2027
Lead sponsor
Washington University School of Medicine
Diseases
Asthma
NCT number
NCT07241117

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 2000
  • From 6 Jan 2026 to the primary completion date, 15 Nov 2027
  • 7 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • The study population can be viewed from the cluster (clinic), clinician, staff, or patient level.
  • At the cluster (clinic) level: To be eligible to participate in this study, a cluster (clinic) must meet all the following criteria:
  • (1) Clinics within participating health systems (Affinia Healthcare and Family Care Health Centers) will be considered eligible if they provided care to ≥100 patients aged ≥12 years with asthma (ICD-10-CM: J45.xx) during the calendar year preceding implementation (2024).
  • At the clinician level:
  • Clinicians will be considered eligible if they:
  • are physicians, nurse practitioners, or physician assistants;
  • are actively employed at a participating clinic during the implementation period; and
  • provided care to ≥10 patients aged ≥12 years with asthma (ICD-10-CM: J45.xx) during the 12 months preceding implementation.
    • At the staff level:
    • Staff will be considered eligible if they:
  • are actively employed at a participating clinic during the implementation period; and
  • directly support clinical care delivery for patients aged ≥12 years with asthma.
    • At the patient level:
    • Patients will be considered eligible if they:
  • are aged ≥12 years;
  • received care at a participating clinic during the implementation period; and (3) meet the study-defined definition of moderate-to-severe asthma based on diagnosis codes, medication use, and/or exacerbation history as defined in the study protocol.

Age in the registry: 12 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (7)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Affinia healthcare, 3396 Pershall Road,
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting
Affinia healthcare, 4414 North Florissant Avenue
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting
Washington University in St. Louis, School of Medicine
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting
Affinia healthcare, 2220 Lemp Ave
Coordinator of this site? Confirm its status
St LouisUnited StatesNot yet recruiting
Family Care Heath Center, 4352 Manchester Ave
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting
Family Care Heath Center, 401 Holly Hills Ave
Coordinator of this site? Confirm its status
St LouisUnited StatesNot yet recruiting
Affinia healthcare, 1717 Biddle Street
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.