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NCT07241663Recruiting

Surgery for Locally Unresectable Pancreatic Cancer

Conversion Surgery for Locally Unresectable Pancreatic Cancer - International Multi-center Observational Trial (ROBIN= suRgery for lOcally unresectaBle pancreatIc Cancer)

Source: ClinicalTrials.gov · Last updated 26 Nov 2025

Brief summary (registry, in English)

Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients treated at expert centers.

Status (registry)
Recruiting
Study type
Observational
Enrollment
150 (estimated)
First submitted
17 Nov 2025
Start date
1 Jan 2025
Primary completion date
31 Dec 2026
Lead sponsor
Azienda Ospedaliera di Padova
NCT number
NCT07241663

What you commit to

  • Study type: Observational
  • Planned participants: 150
  • From 1 Jan 2025 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Presence of tumor characteristics precluding surgery
  • Presence of patient significant comorbidities precluding surgery
  • Unavailable pre-induction therapy abdominal imaging

Other

  • Informed consent withdrawal
  • Pathological confirmation of any tumor different from PDAC

Who the study is looking for

  • Patients older than 18 years
  • Patients able to give informed consent
  • Histologically confirmed pancreatic adenocarcinoma
  • LAPC stage according to NCCN10 at diagnosis (Figure 1)
  • Received at least 4 months of induction chemotherapy
  • RECIST 1.1 stable disease (SD) or partial response (PR) after induction therapy
  • Patient considered eligible for radical resection by local MDT

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UOC Chirurgia Generale 2, Azienda Ospedale di Padova, Padova, Italy 35128
Coordinator of this site? Confirm its status
PadovaItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.