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NCT07242027Completed

Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Patients

Lactate-to-albumin, CRP-to-albumin and Procalcitonin-to-albumin Ratios Predict Mortality in Critically Ill Adults: a Retrospective ICU Cohort Study

Source: ClinicalTrials.gov · Last updated 21 Nov 2025

Brief summary (registry, in English)

This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B at the Silesian Center for Heart Diseases (SCCS) in Zabrze. Researchers will analyze retrospective clinical and laboratory data from electronic medical records, including lab values collected at ICU admission, patient demographics, diagnoses, and outcomes. The biomarker ratios will be manually calculated in Excel and statistically evaluated. The main goal is to assess whether these ratios are associated with patient survival and to identify predictive cut-off values to support early risk stratification in the ICU setting.

Status (registry)
Completed
Study type
Observational
Enrollment
212 (actual)
First submitted
15 Sept 2025
Start date
21 Mar 2025
Primary completion date
25 Jul 2025
Lead sponsor
Medical University of Silesia
NCT number
NCT07242027

What you commit to

  • Study type: Observational
  • Participants enrolled: 212
  • From 21 Mar 2025 to the primary completion date, 25 Jul 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Lab values

  • Lack of laboratory parameters necessary for ratio calculation

Other

  • Missing outcome data (e.g. unknown survival status)

Who the study is looking for

  • Age ≥ 18 years
  • Admission to ICU in 2024
  • Availability of data for lactate, CRP, procalcitonin, and albumin

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Acute Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland
Coordinator of this site? Confirm its status
ZabrzePolandUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.