NCT07242326Enrolling by invitation
SNAP AF-52: Dose Appropriateness and Adherence to Oral Anticoagulation in Adults ≥65 With Atrial Fibrillation in Primary Care (Ordu, Türkiye)
SNAP AF-52 - An Ambidirectional Observational Study to Assess Label-Concordant Dosing and Medication Adherence (Proportion of Days Covered) for Oral Anticoagulants in Adults Aged ≥65 Years With Atrial Fibrillation Managed in Family Health Centers in Ordu, Türkiye, With Same-Day Tertiary Cardiology Referral for Unsafe Findings
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
SNAP AF-52 is an ambidirectional observational registry conducted in family health centers (primary care) across Ordu, Türkiye, enrolling adults ≥65 years with a pre-existing diagnosis of atrial fibrillation. The study assesses (a) label-concordant dosing of oral anticoagulants (DOACs/warfarin) using drug-specific criteria, and (b) medication adherence via Proportion of Days Covered (PDC) over the prior 12 months (good adherence defined as PDC ≥80%). Unsafe findings (e.g., suspected under-/overdosing, critical drug-drug interactions, very low renal function) trigger same-day referral to tertiary cardiology for evaluation and management. The retrospective window is Dec 1, 2024-Nov 30, 2025; the prospective single-visit inclusion window is Dec 1, 2025-May 31, 2026. No experimental treatment is administered; all care is routine.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 15 Dec 2025
- Primary completion date
- 30 Dec 2026
- Lead sponsor
- Kotyora Family Medicine Health Management and Education Association
- Diseases
- Atrial fibrillation
- NCT number
- NCT07242326
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 15 Dec 2025 to the primary completion date, 30 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in an interventional drug study affecting anticoagulation
Other illness
- Mechanical prosthetic heart valve or moderate-to-severe rheumatic mitral stenosis
Lab values
- Lack of minimal data elements required for dose classification (age, sex, body weight, serum creatinine with date, current OAC and regimen)
Other
- Investigator judgment that reliable data cannot be obtained from records
Who the study is looking for
- Age ≥65 years.
- Established atrial fibrillation (any type) documented in the medical record.
- Presenting to a family health center (primary care) in Ordu province during the prospective window or having records within the retrospective window.
- On an oral anticoagulant (DOAC) at any time in the 12-month window.
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ordu University Faculty of Medicine, Department of Cardiology Coordinator of this site? Confirm its status | Ordu | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.