NCT07242573Recruiting
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Evaluation of the Effect of Individualized Physical Training and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 24 Feb 2026
Brief summary (registry, in English)
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using diagnostic-training devices (Zebris treadmill and Alfa balance platform) and transcutaneous neuromodulation (NESA X-Signal) on pain, sleep quality, and overall health status in patients with fibromyalgia and chronic fatigue symptom. Participants are allocated into three groups: 1. Physical training + conventional physiotherapy, 2. Transcutaneous neuromodulation + conventional physiotherapy, 3. Control (conventional physiotherapy only). The results will support the development of evidence-based rehabilitation protocols for fibromyalgia patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 20 Feb 2027
- Lead sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT07242573
What you commit to
- Study type: Interventional
- Planned participants: 75
- From 1 Nov 2025 to the primary completion date, 20 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cancer
- Neurological disorders (e.g., neuralgia, multiple sclerosis, diabetic polyneuropathy, stroke)
- Diagnosed dementia or cognitive impairment
- Internal bleeding or acute febrile illness
- Infectious skin diseases (e.g., mycosis, purulent dermatitis)
Other
- Lack of informed consent or cooperation
- Refusal to undergo procedures beyond standard NFZ physiotherapy
- Implanted electronic devices (e.g., pacemaker)
- Acute thrombophlebitis
- Hysteria or electric phobia
- Neurotic addiction to stimulation
- Inability to communicate in Polish sufficiently to complete questionnaires or follow instructions
Who the study is looking for
- Age between 20 and 80 years
- Confirmed diagnosis of fibromyalgia
- Presence of chronic fatigue symptoms
- Stable health condition
- Presence of sleep disturbances
- Ability to provide written informed consent and cooperate during the study
Age in the registry: 20 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rehabilitation Clinic, National Institute of Geriatrics, Rheumatology and Rehabilitation (NIGRiR) Coordinator of this site? Confirm its status | Warsaw | Poland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.