NCT07243795Not yet recruiting
Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy
Impact of Preoperative Ejaculation or Abstinence on Seminal Vesicle Size and Intraoperative Dissection Parameters During Radical Prostatectomy: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 3 Dec 2025
Brief summary (registry, in English)
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are: Does ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more? Does seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy? Researchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them. Participants will: Follow specific instructions to either ejaculate or abstain before surgery Undergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery Have their surgical dissection time and difficulty rated by the operating surgeon
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 17 Nov 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Prostate cancer
- NCT number
- NCT07243795
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Dec 2025 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior bilateral seminal vesicle resection or congenital absence of seminal vesicles
- Hormone therapy within 6 months before surgery
- Prior prostate cancer treatment
Other illness
- Severe anorectal disease or history of anorectal surgery preventing TRUS
- Cognitive or psychiatric conditions impairing informed consent
Other
- Anatomical abnormalities preventing SV identification
- Inability to recall ejaculation history in the past 3 days
- Inability to follow behavioral instructions or TRUS protocol
- Incomplete data or poor-quality imaging
- Belonging to a vulnerable population (e.g., minors, prisoners, pregnant individuals, cognitively impaired, etc.)
Who the study is looking for
- Male patients aged 18 years or older
- Histologically confirmed prostate cancer
- Scheduled for radical prostatectomy
- Able and willing to comply with assigned ejaculation or abstinence protocol
- Willing to complete preoperative questionnaire
- Willing to undergo transrectal ultrasound (TRUS) 12-14 hours before surgery
- Able to understand and sign informed consent
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Cancer Center Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.